Table 2 Association of variables with progression of carcinoid heart disease

From: Serial surveillance of carcinoid heart disease: factors associated with echocardiographic progression and mortality

Variable

Progression of carcinoid heart disease ( n =13)

No progression of carcinoid heart disease ( n =95)

P -value

Symptomatic deteriorationa

11 (85%)

5 (5%)

<0.001

NT-proBNP progressionb

8 (62%)

24 (31%)

0.04

Plasma 5-HIAA progressionb

6 (46%)

14 (18%)

0.035

Radiological progressionc

4 (31%)

35 (37%)

0.461

  1. a>50% increase in the number of daily flushing episodes or bowel movements compared with the previous visit.
  2. b>50% increase from the baseline value.
  3. cin accordance with RECIST (Response Evaluation Criteria in Solid Tumors) guidelines. Significant P-values (<0.05) are indicated in bold.