Table 1 Clinicopathological characteristics of recruited subjects

From: microRNA-221 and microRNA-18a identification in stool as potential biomarkers for the non-invasive diagnosis of colorectal carcinoma

Category

Normal

Adenoma

AA

CRC

No. of cases

198

151

48

198

Age at enrolment, years (mean±s.d.)

58.65±6.87

60.39±5.65

58.73±6.78

66.53±11.05

Gender, no. (%)

Male

84 (42%)

83 (55%)

31 (65%)

116 (59%)

Female

114 (58%)

68 (45%)

17 (35%)

82 (41%)

Location a , no. (%)

Proximal

  

20 (41.7%)

50 (25.3%)

Distal (excluding rectum)

  

18 (37.5%)

82 (41.4%)

Rectum

  

8 (16.6%)

66 (33.3%)

Othersb

  

2 (4.2%)

0

CRC staging

I+II

   

106 (53.5%)

III+IV

   

88 (44.5%)

Unknown

   

4 (2.0%)

Antibiotic intake, no. (%)

Yes

   

26 (13%)

No

   

172 (87%)

  1. Abbreviations: AA=advanced adenoma; CRC=colorectal carcinoma.
  2. aColorectal neoplasms were classified by three locations: proximal colon (caecum, ascending, hepatic flexure, and transverse), distal colon (splenic flexure, descending, sigmoid, and recto-sigmoid junction) and rectum.
  3. bThe carcinomas or advance adenomas were found in more than one location.
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