Table 3 The correlation between miR-183 expression and clinical variables of ESCC patients
miR-183 expression (2−ΔΔCt) | ||||
---|---|---|---|---|
Variables | All cases (%) | High expression ( n) | Low expression ( n) | P -value |
Total number | 62 | |||
Age | ||||
>60 | 39 (62.9) | 19 | 0.79 | |
⩽60 | 23 (37.1) | 12 | 11 | |
Gender | ||||
Male | 46 (74.2) | 22 | 0.56 | |
Female | 16 (25.8) | 9 | 7 | |
Degree of tumour differentiation | ||||
Cancer | 32 (51.6) | 20 | 0.11 | |
HG-IEN | 21 (33.9) | 7 | 14 | |
LG-IEN | 9 (14.5) | 4 | 5 | |
Tumour location | ||||
Upper middle | 38 (61.3) | 20 | 0.4 | |
Lower | 24 (38.7) | 10 | 14 | |
Tumour size | ||||
>3 × 3 × 3 cm | 6 (9.7) | 4 | 0.06 | |
⩽3 × 3 × 3 cm | 56 (90.3) | 16 | 40 | |
TNM stage | ||||
I/II | 48 (77.4) | 21 | 0.59 | |
III/IV | 14 (22.6) | 5 | 9 | |
Tumour stage | ||||
T0 | 30 (48.4) | 11 | 0.08 | |
T1 | 7 (11.3) | 6 | 1 | |
T2 | 4 (6.5) | 1 | 3 | |
T3 | 20 (32.3) | 12 | 8 | |
T4 | 1 (1.5) | 1 | 0 | |
Lymphatic metastasis | ||||
Positive | 11 (17.7) | 7 | 0.11 | |
Negative | 51 (82.3) | 19 | 32 |