Table 2 Crude and adjusted HR for type 2 diabetes between the breast cancer and control groups

From: Association of tamoxifen use and increased diabetes among Asian women diagnosed with breast cancer

 

Control

Breast cancer

Breast cancer without using tamoxifen

Breast cancer using tamoxifen

No. of type 2 diabetes

8232

2082

574

1508

Person-years

723 286.28

158 563.47

47 714.87

110 848.61

IR

11.38

13.13

12.03

13.60

Crude HR (95% CI)

1.00

1.15 (1.10–1.21)***

1.06 (0.97–1.15)

1.19 (1.13–1.26)***

Adjusted HR (95% CI)a

1.00

1.14 (1.08–1.20)***

1.05 (0.96–1.14)

1.18 (1.11–1.24)***

Crude HR (95% CI)

  

1.00

1.13 (1.03–1.25)*

Adjusted HR (95% CI)b

  

1.00

1.31 (1.19–1.45)***

  1. Abbreviations: CI=confidence interval; HR=hazard ratio; IR=incidence density rates per 1000 person-years. *P<0.05, ***P<0.001.
  2. aAdjusted for age, insured amount, comorbidity, steroids, thiazide diuretics, and statins.
  3. bAdjusted for age, insured amount, comorbidity, steroids, thiazide diuretics, statins, operations on the breast, chemotherapy, radiotherapy, and aromatase inhibitor.
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