Table 1 Clinicopathological data for patients and healthy controls
From: Serum microRNA panel as biomarkers for early diagnosis of colorectal adenocarcinoma
Characteristics | Screening phase | Training phase | Validation phase |
|---|---|---|---|
Healthy control | |||
N | 30 | 94 | 102 |
Age (mean±s.d.), years | 54.37±16.24 | 52.33±13.16 | 52.76±11.36 |
Sex, n (%) | |||
Male | 18 (60.0) | 51 (54.3) | 59 (57.8) |
Female | 12 (40.0) | 43 (45.7) | 43 (42.2) |
CA | |||
Number | 25 | 66 | 73 |
Age (mean±s.d.), years | 54.60±17.36 | 51.31±10.80 | 52.43±12.38 |
Sex, n (%) | |||
Male | 16 (64.0) | 39 (59.1) | 42 (57.5) |
Female | 9 (36.0) | 27 (40.9) | 31 (42.5) |
Location of adenoma, n (%) | |||
Colon | 18 (72.0) | 46 (69.7) | 53 (72.6) |
Rectum | 7 (28.0) | 20 (30.3) | 20 (27.4) |
Adenoma grade, n (%) | |||
Low-grade intraepithelial neoplasia | 14 (56) | 42 (63.6) | 39 (53.4) |
High-grade intraepithelial neoplasia | 11 (44) | 24 (36.4) | 34 (46.6) |
CAC | |||
Number | 30 | 160 | 117 |
Age (mean±s.d.), years | 56.56±19.67 | 60.19±13.54 | 56.28±14.72 |
Sex, n (%) | |||
Male | 19 (63.3) | 93 (58.1) | 68 (58.2) |
Female | 11 (36.7) | 67 (41.9) | 49 (41.8) |
Location of tumours, n (%) | |||
Colon | 22 (73.3) | 112 (70.0) | 83 (70.9) |
Rectum | 8 (26.7) | 48 (30.0) | 34 (29.1) |
Tumour size, n (%) | |||
⩽3 cm | 4 (13.3) | 26 (16.3) | 18 (15.4) |
>3 cm | 26 (86.7) | 134 (83.7) | 99 (84.6) |
Differentiation, n (%) | |||
Well | 4 (13.3) | 34 (21.3) | 18 (15.4) |
Moderate | 19 (63.3) | 91 (56.9) | 76 (65.0) |
Poor | 5 (16.7) | 35 (21.8) | 23 (19.6) |
N/A | 2 (6.7) | ||
TNM stage, n (%) | |||
Stage I | 11 (36.7) | 23 (14.4) | 19 (16.2) |
Stage II | 8 (26.6) | 49 (30.6) | 31 (26.5) |
Stage III | 5 (16.7) | 71 (44.4) | 46 (39.3) |
Stage IV | 4 (13.3) | 17 (10.6) | 21 (18.0) |
N/A | 2 (6.7) | ||
