Table 4 Research indices in 16 patients in group 1 (surgery only)

From: Effect of standard chemotherapy and antiangiogenic therapy on plasma markers and endothelial cells in colorectal cancer

 

Baseline

3 months

6 months

P -value

Circulating endothelial cells (cells ml−1)

4 (0–19)

0 (0–9)

8 (0–10)

0.045

Endothelial progenitor cells (cells ml−1)

13 (0–39)

0 (0–9)

8 (0–10)

0.036a

Von Willebrand factor (IU dl−1)

115 (22)

106 (19)

118 (30)

0.441

Soluble E selectin (ng ml−1)

31 (9)

26 (9)

29 (11)

0.302

VEGF (pg ml−1)

120 (10–494)

23 (6–23)

16 (5–82)

0.024b

Angiogenin (ng ml−1)

308 (75)

235 (97)

300 (96)

0.061

CD34+ve cells (cells ml−1)

849 (638–1167)

1083 (679–1603)

918 (500–1269)

0.395

White cell count (x106ml−1)

6.7 (1.6)

5.7 (1.7)

6.2 (1.3)

0.175

  1. Data are mean (s.d.) or median (interquartile range). P-value by ANOVA.
  2. aP<0.05, baseline to 3-month point.
  3. bP<0.05, baseline to 3-month and 6-month points.
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