Table 4 Multivariate analysis for PFS and OS

From: PKM2 as a biomarker for chemosensitivity to front-line platinum-based chemotherapy in patients with metastatic non-small-cell lung cancer

 

Hazard ratio

95% CI

P -value

PFS

PKM2 expression (high vs low)

1.81

1.40–2.38

0.002

PS (2 vs 0–1)

3.97

2.77–4.16

<0.001

Stage (IV vs IIIB)

1.34

0.96–1.88

0.13

OS

PKM2 expression (high vs low)

1.97

1.45–2.46

0.001

PS (2 vs 0–1)

4.01

3.56–5.06

<0.001

  1. Abbreviations: CI=confidence interval; OS=overall survival; PFS=progression-free survival; PS=performance status.
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