Table 3 Correlation between cytological diagnoses and P53 staining of capsule sponge specimens and pathological diagnoses of endoscopic biopsy samples from the oesophagus in 301 asymptomatic subjects from Golestan Province, Iran
Cytological diagnoses | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Histological diagnoses | Normal | ASCUS | ASC | Total | P53 positivity | |||||
N | % | N | % | N | % | N | % | N | % | |
Normal | 165 | 91.2 | 12 | 6.6 | 4 | 2.2 | 181 | 60.1 | 23 | 12.7 |
Basal cell hyperplasia | 5 | 100.0 | 0 | 0.0 | 0 | 0.0 | 5 | 1.7 | 3 | 60.0 |
Mild esophagitis | 64 | 98.5 | 1 | 1.5 | 0 | 0.0 | 65 | 21.6 | 4 | 6.2 |
Moderate esophagitis | 15 | 93.8 | 1 | 6.3 | 0 | 0.0 | 16 | 5.3 | 2 | 12.5 |
Severe esophagitis | 6 | 85.7 | 1 | 14.3 | 0 | 0.0 | 7 | 2.3 | 0 | 0.0 |
Atypical changes indefinite for dysplasia | 4 | 44.4 | 5 | 55.6 | 0 | 0.0 | 9 | 3.0 | 0 | 0.0 |
Mild squamous dysplasia | 7 | 50.0 | 2 | 14.3 | 5 | 35.7 | 14 | 4.7 | 0 | 0.0 |
Moderate squamous dysplasia | 0 | 0.0 | 0 | 0.0 | 2 | 100.0 | 2 | 0.7 | 2 | 100.0 |
Severe squamous dysplasia | 0 | 0.0 | 0 | 0.0 | 2 | 100.0 | 2 | 0.7 | 2 | 100.0 |
Total | 266 | 88.4 | 22 | 7.3 | 13 | 4.3 | 301 | 100.0 | 36 | 12.0 |
