Figure 1 | British Journal of Cancer

Figure 1

From: Interrogation of gossypol therapy in glioblastoma implementing cell line and patient-derived tumour models

Figure 1

Gossypol reduces endothelial and GBM cell viability in a dose-dependent manner. (A) The human GBM cell lines (U251, U373, U343, U87MG-luc2) and (B) HUVECs were exposed to various concentrations of gossypol for 72 h. GBM/endothelial cell viability was assessed using the MTT-based cell viability assay. Each treatment condition was replicated in at least three wells and in three independent experiments. (C) IC50 concentrations were estimated based on sigmoidal dose–response curves using the GraphPad software. Mean±s.e.m. of three independent experiments are presented.

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