Figure 1 | British Journal of Cancer

Figure 1

From: B-RAF mutation and accumulated gene methylation in aberrant crypt foci (ACF), sessile serrated adenoma/polyp (SSA/P) and cancer in SSA/P

Figure 1

Endoscopic and histologic features of SSA/P ( A and B ) and ACF ( C and D ) in the right-side colon. (A) Representative endoscopic view of SSA/P with 10 mm diameter. The size was estimated using biopsy forceps. (B) Histological examination showed serration in the lower crypt, and distorted, dilated, or anchor-shaped crypts (H&E staining). (C) Representative endoscopic view of ACF in the right-side colon from the same patient (case 7). ACF were identified by methylene blue staining under magnifying endoscopy. ACF consisted of larger and more darkly stained crypts than normal crypts. (D) Histological examinations showed serration and distortion of the crypts (H&E staining).

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