Table 1A Top 20 genes that are induced by EGR3 in M12 cells (i.e., genes for which expression was lower in shEGR3-M12-silenced cells compared with shSCR-M12 control cells)

From: Early Growth Response 3 regulates genes of inflammation and directly activates IL6 and IL8 expression in prostate cancer

	Gene name	Gene symbol	Probe ID	Fold change	P- value
1	Pentraxin-related gene, rapidly induced by IL-1β	PTX3	206157_at	−105.94	6E−09
2	Oxidised low-density lipoprotein (lectin-like) receptor 1	OLR1	210004_at	−100.22	2E−09
3	Keratin 34	KRT34	206969_at	−86.04	3E−09
4	Microfibrillar associated protein 5	MFAP5	209758_s_at	−85.61	4E−08
			213764_s_at	−27.52	6E−09
			213765_at	−14.57	9E−08
5	Monoamine oxidase A	MAOA	204388_s_at	−67.5	2E−09
			204389_at	−37.76	1E−07
			212741_at	−37.24	2E−07
6	Chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, α)	CXCL1	204470_at	−57.03	7E−08
7	Regulating synaptic membrane exocytosis 2	RIMS2	229823_at	−49.26	1E−09
			206137_at	−15.91	5E−07
8	Gap junction protein, α1, 43 kDa	GJA1	201667_at	−41.7	3E−08
9	Tissue factor pathway inhibitor 2	TFPI2	209278_s_at	−36.22	6E−09
			209277_at	−8.44	8E−06
10	Membrane metallo-endopeptidase	MME	203434_s_at	−28.88	3E−06
			203435_s_at	−6.27	2E−07
11	Complement component 4 binding protein,β	C4BPB	208209_s_at	−23.48	9E−08
12	Doublecortin and CaM kinase-like 1	DCAMKL1	205399_at	−22.96	6E−09
13	Lymphotoxin β (TNF superfamily, member 3)	LTB	207339_s_at	−19.29	1E−08
14	Chemokine (C-C motif) ligand 20	CCL20	205476_at	−18.71	6E−08
15	A kinase (PRKA) anchor protein 12	AKAP12	227529_s_at	−18.38	5E−08
			227530_at	−14.76	3E−08
			210517_s_at	−11.06	7E−07
			231067_s_at	−3.4	0.0001
16	Chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	CXCL6	206336_at	−18.11	2E−06
17	Doublecortin-like kinase 1	DCLK1	229800_at	−17.89	2E−08
18	DENN/MADD domain containing 4B	DENND4B	202860_at	−17.54	2E−07
19	Interleukin 8	IL8	211506_s_at	−17.34	3E−07
20	Protocadherin 7	PCDH7	205534_at	−17.22	2E−07
			228640_at	−12.83	4E−07

Abbreviation: EGR3=Early Growth Response 3.

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Table 1A Top 20 genes that are induced by EGR3 in M12 cells (i.e., genes for which expression was lower in shEGR3-M12-silenced cells compared with shSCR-M12 control cells)

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