Table 1B Top 20 genes that are repressed by EGR3 in M12 cells (i.e., genes for which expression was higher in shEGR3-M12-silenced cells compared with shSCR-M12 control cells)
Gene name | Gene symbol | probe ID | Fold change | P- value | |
|---|---|---|---|---|---|
1 | Colorectal neoplasia differentially expressed (non-protein coding) | CRNDE | 1552797_s_at | 32.28 | 2E−08 |
2 | H19, imprinted maternally expressed transcript (non-protein coding) | H19 | 1562019_at | 24.59 | 2E−08 |
200884_at | 22.93 | 8E−09 | |||
3 | S100 calcium binding protein A2 | S100A2 | 201331_s_at | 11.6 | 8E−08 |
4 | Cytochrome P450, family 4, subfamily X, polypeptide 1 | CYP4X1 | 201641_at | 10.48 | 6E−08 |
5 | Protease, serine, 3 | PRSS3 | 201820_at | 8.784 | 3E−07 |
202437_s_at | 8.062 | 8E−08 | |||
6 | Phosphatidic acid phosphatase type 2 domain containing 1A | PPAPDC1A | 202504_at | 8.618 | 2E−06 |
7 | Solute carrier family 2 (facilitated glucose transporter), member 10 | SLC2A10 | 203381_s_at | 7.59 | 3E−05 |
8 | Desmoglein 3 (pemphigus vulgaris antigen) | DSG3 | 203382_s_at | 6.705 | 4E−05 |
9 | Bone morphogenetic protein 2 | BMP2 | 203543_s_at | 6.648 | 2E−06 |
203729_at | 5.956 | 9E−06 | |||
10 | Sialic acid acetylesterase | SIAE | 204225_at | 5.906 | 3E−06 |
11 | Potassium large conductance calcium-activated channel, subfamily M, α member 1 | KCNMA1 | 204268_at | 5.868 | 5E−07 |
12 | Sulfotransferase family 1E, oestrogen-preferring, member 1 | SULT1E1 | 204455_at | 5.236 | 4E−06 |
13 | Spleen tyrosine kinase | SYK | 204537_s_at | 5.147 | 1E−05 |
204540_at | 4.367 | 1E−06 | |||
14 | Growth factor receptor-bound protein 10 | GRB10 | 204783_at | 4.709 | 1E−05 |
15 | S100 calcium binding protein A14 | S100A14 | 204955_at | 4.474 | 3E−06 |
16 | Chemokine (C-X-C motif) receptor 7 | CXCR7 | 205128_x_at | 4.365 | 8E−05 |
17 | Shisa homolog 2 (Xenopus laevis) | SHISA2 | 205157_s_at | 4.321 | 5E−05 |
18 | UDP glucuronosyltransferase 1 family, polypeptide A3; polypeptide A5; polypeptide A4; polypeptide A7; polypeptide A6; polypeptide A10; polypeptide A9; polypeptide A8; polypeptide A1 | UGT1A | 205289_at | 4.305 | 6E−06 |
205290_s_at | 3.242 | 1E−05 | |||
205319_at | 3.074 | 3E−06 | |||
205559_s_at | 2.656 | 2E−05 | |||
19 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | DDX60 | 205730_s_at | 4.269 | 6E−07 |
20 | Prostate stem cell antigen | PSCA | 205885_s_at | 4.061 | 3E−06 |
