Figure 6

Treatment-induced increases in AUC_1 min, FEV_1 min and K^trans indicate a change in vascular function in both TOV-21G and TOV-112D xenografts. (A) Change in AUC_1 min, (B) change in FEV_1 min and (C) change in K^trans for treatment and control groups of both TOV-21G and TOV-112D xenografts. Independent sample t-test BEZ235 (Tx) vs control: ^#P<0.05, ^##P<0.01. Paired sample t-test day 0 vs day 3: *P<0.05.