Table 1 Clinical patient characteristics, n=559
Age at first diagnosis | |
Median, years | 49 |
Range | (14–92) |
FIGO stage | |
IA/B | 279 (49.9%) |
IC | 134 (24.0%) |
IIA-C | 65 (11.6%) |
IIIA-C | 81 (14.5%) |
Primary surgical approach | |
Laparoscopy | 198 (35.4%) |
Converted laparoscopy | 54 (9.7%) |
Laparotomy | 307 (54.9%) |
Histologic characteristics | |
Stromal microinvasion | 30 (5.4%) |
Micropapillary pattern | 85 (15.2%) |
Surgical procedures in primary and re-staging surgery a | |
Bilateral salpingo-oophorectomy | 450 (80.5%) |
Unilateral salpingo-oophorectomy | 135 (24.2%) |
Cystectomy | 103 (18.4%) |
Hysterectomy | 398 (71.2%) |
Omentectomy | 438 (78.4%) |
Peritoneal biopsies | 374 (66.9%) |
Cytology | 382 (68.3%) |
Appendectomy | 165 (29.5%) |
Pelvic LND/LN biopsies | 118 (21.1%) |
Para-aortic LND/LN biopsies | 77 (13.8%) |
Peritoneal implants in primary or re-staging surgery | |
None | 428 (76.6%) |
Non-invasive | 110 (19.7%) |
Invasive | 21 (3.8%) |
Surgical cytoreduction | |
Complete | 517 (92.5%) |
Incomplete | 8 (1.4%) |
Unknown | 34 (6.1%) |
Staging quality after primary surgery | |
Adequate | 164 (29.3%) |
Inadequate | 395 (70.7%) |
Staging quality after primary and re-staging surgery | |
Adequate | 278 (49.7%) |
Inadequate | 281 (50.3%) |
Fertility-sparing surgery | |
Yes | 110 (19.7%) |
No | 449 (80.3%) |
Up-staging after re-staging surgery | |
Yes | 29 (5.2%) |
No | 530 (94.8%) |
Recurrent disease | |
Yes | 53 (9.5%) |
Borderline tumour | 40/53 (75.5%) |
High grade carcinoma | 4/53 (7.5%) |
Low grade carcinoma | 8/53 (15.1%) |
Unknown | 1/53 (1.9%) |
No | 506 (90.5%) |
Site of recurrent disease a | |
Ovarian tissue | 26/53 (49.1%) |
Ipsilateral | 9/53 (17.0%) |
Contralateral | 20/53 (37.7%) |
Peritoneum | 28/53 (52.8%) |
Omentum | 1/53 (1.9%) |
Other | 2/53 (3.8%) |
Unknown | 10/53 (18.9%) |
Malignant transformation during follow-up | |
Yes | 13/53 (24.5%) |
No | 40/53 (75.5%) |
5-year progression-free survival | 86.9% |
5-year disease-specific survival | 99.2% |
