Table 4 Multivariate analyses of potential prognostic factors for overall survival in patients undergoing first-line chemotherapy incorporating hCGβ level either before, or on completion of, chemotherapy
Factor | HR | 95% CI | P -value | HR | 95% CI | P -value |
|---|---|---|---|---|---|---|
ECOG PS | ||||||
⩾2 vs 0 or 1 | 2.39 | 1.38–4.13 | 0.002 | 2.09 | 1.01–4.33 | 0.047 |
ALP | ||||||
<LLN vs ⩾LLN | 0.98 | 0.59–1.60 | 0.92 | 1.44 | 0.78–2.68 | 0.24 |
Visceral metastases | ||||||
Yes vs no | 2.01 | 1.29–3.13 | 0.002 | 2.65 | 1.49–4.70 | 0.001 |
Chemotherapy regimen | ||||||
GCarbo vs GC | 0.83 | 0.83–0.66 | 0.11 | 1.86 | 0.52–6.66 | 0.34 |
Prior perioperative chemotherapy | ||||||
Yes vs no | 2.16 | 0.81–5.79 | 0.82 | 1.07 | 0.60–6.66 | 0.34 |
hCG β level before chemotherapy | ||||||
⩾2 vs <2 IU l−1 | 1.28 | 0.84–1.96 | 0.25 | — | — | — |
hCG β level on completion of chemotherapy | ||||||
⩾2 vs <2 IU l−1 | — | — | — | 3.47 | 1.97–6.10 | 0.00002 |
