Table 3 Association between long-term heavy smoking and CRC deaths

From: Association between smoking and deaths due to colorectal malignant carcinoma: a national population-based case–control study in China

 

Non-smokers

Mild-medium smokers

Long-term heavy smokers

 
 

Control (%)

Case (%)

Control (%)

Case (%)

OR (95% CI) a

Control (%)

Case (%)

OR (95% CI) a

P for trend

Urban men

4510 (43.90)

2180 (42.44)

4112 (40.02)

1960 (38.15)

0.984 (0.913–1.060)

1652 (16.08)

997 (19.41)

1.250 (1.138–1.373)

<0.001

 Foreland region in north China

1360 (48.89)

657 (47.23)

1101 (39.58)

546 (39.25)

1.024 (0.890–1.178)

321 (11.54)

188 (13.52)

1.212 (0.990–1.485)

0.109

 Foreland region in south China

1760 (43.35)

902 (44.43)

1512 (37.24)

644 (31.72)

0.829 (0.733–0.937)

788 (19.41)

484 (23.84)

1.202 (1.046–1.382)

0.110

 Inland region in north China

571 (50.44)

270 (47.70)

449 (39.66)

231 (40.81)

1.085 (0.874–1.347)

112 (9.89)

65 (11.48)

1.235 (0.880–1.732)

0.208

 Inland region in south China

819 (35.61)

351 (30.52)

1050 (45.65)

539 (46.87)

1.198 (1.018–1.411)

431 (18.74)

260 (22.61)

1.401 (1.149–1.710)

0.001

Urban women

8322 (83.40)

4108 (82.34)

1427 (14.30)

708 (14.19)

0.996 (0.903–1.098)

229 (2.30)

173 (3.47)

1.512 (1.236–1.850)

<0.001

 Foreland region in north China

1951 (75.97)

946 (73.68)

548 (21.65)

278 (21.34)

1.043 (0.885–1.229)

69 (2.69)

60 (4.67)

1.800 (1.262–2.568)

0.016

 Forland region in south China

3501 (84.57)

1754 (84.73)

537 (12.97)

246 (11.88)

0.897 (0.762–1.055)

102 (2.46)

70 (3.38)

1.344 (0.985–1.833)

0.538

 Inland region in north China

969 (85.75)

476 (84.25)

141 (12.48)

71 (12.57)

1.015 (0.747–1.379)

20 (1.77)

18 (3.19)

1.796 (0.939–3.437)

0.188

 Inland region in south China

1901 (88.83)

932 (87.10)

201 (9.39)

113 (10.56)

1.138 (0.891–1.454)

38 (1.78)

25 (2.34)

1.321 (0.792–2.205)

0.123

Rural men

1132 (37.14)

480 (31.50)

1454 (47.70)

732 (48.03)

1.193 (1.037–1.372)

462 (15.16)

312 (20.47)

1.604 (1.341–1.919)

<0.001

 Foreland region in north China

142 (52.59)

68 (50.37)

106 (39.26)

54 (40.00)

1.062 (0.682–1.652)

22 (8.15)

13 (9.63)

1.222 (0.579–2.577)

0.587

 Foreland region in south China

522 (33.12)

214 (27.16)

731 (46.38)

364 (46.19)

1.205 (0.993–1.498)

323 (20.49)

210 (26.65)

1.598 (1.262–2.024)

<0.001

 Inland region in north China

254 (42.19)

111 (36.88)

305 (50.66)

156 (51.83)

1.183 (0.878–1.592)

43 (7.14)

34 (11.30)

1.854 (1.120–3.069)

0.031

 Inland region in south China

214 (35.67)

87 (29.00)

312 (52.00)

158 (52.67)

1.245 (0.909–1.705)

74 (12.33)

55 (18.33)

1.796 (1.166–2.768)

0.007

Rural women

2364 (91.49)

1168 (90.40)

205 (7.93)

110 (8.51)

1.074 (0.843–1.369)

15 (0.58)

14 (1.08)

1.864 (0.896–3.876)

0.016

 Foreland region in north China

227 (91.53)

112 (90.32)

20 (8.06)

11 (8.87)

1.115 (0.516–2.407)

1 (0.40)

1 (0.81)

1.926 (0.119–31.184)

 Foreland region in south China

1375 (91.91)

680 (90.91)

109 (7.29)

58 (7.75)

1.076 (0.772–1.499)

12 (0.8)

10 (1.34)

1.665 (0.715–3.876)

0.289

 Inland region in north China

380 (90.91)

185 (88.52)

38 (9.09)

22 (10.53)

1.189 (0.684–2.069)

0

2 (0.96)

 Inland region in south China

382 (90.52)

191 (90.52)

38 (9.00)

19 (9.00)

1.000 (0.561–1.782)

2 (0.47)

1 (0.47)

1.014 (0.091–11.265)

Total

16 328 (63.08)

79.36 (61.32)

7198 (27.81)

3510 (27.12)

1.003 (0.956–1.053)

2358 (9.11)

1496 (11.56)

1.302 (1.214–1.397)

<0.001

  1. Abbreviations: CI=confidence interval; OR=odds ratio.
  2. aAdjusted for age in each stratum and age, sex, and residence in total.