Table 1 Number of cases and associated risks of primary tumours of the CNS, leukaemia, and lymphoma

From: Response to ‘Are the studies on cancer risk from CT scans biased by indication? Elements of answer from a large-scale cohort study in France’

  

CNS cancer

 

Leukaemia

 

Lymphoma

 

Cases

IR

ERR

95% CI a

Cases

IR

ERR

95% CI

Cases

IR

ERR

95% CI

All children

22

9.4

  

17

7.3

  

19

8.1

  

 Unadjusted for predisposing factorsb

  

0.022

−0.016, 0.061

  

0.057

−0.079; 0.193

  

0.018

−0.068; 0.104

 Adjusted for predisposing factors

  

0.012

−0.013, 0.037

  

0.047c

−0.065; 0.159

  

0.008

−0.057; 0.073

Children without a predisposing factor

15

6.4

0.028

n.a.

12

5.2

0.187

n.a.

12

5.2

0.025

n.a.

Children with a predisposing factor

7

565.9

−0.005

n.a.

5

128.0

−0.012

n.a.

7

160.3

−0.005

n.a.

  1. Abbreviations: CNS=central nervous system; CI=confidence interval; ERR=excess relative risk; IR=incidence rate; n.a.=not available.
  2. The table provides the IR per 100 000 person-years, ERR related to cumulative organ dose (in mGy) from CT scans, for all children (without and with adjustment for predisposing factors), and separately for children with and without predisposing factors, with a 2-year exclusion period (based onJourny et al, 2015).
  3. aWald-based CI for the ERR.
  4. bFactors predisposing specifically to cancer at the site specified.
  5. cListed as 0.045 in Supplementary Table 6 of Journy et al.