Table 3 Validation of the MBCSIM model in 108 ER-positive breast cancer patients for a follow-up period of 5 years

From: The value of PET/CT with FES or FDG tracers in metastatic breast cancer: a computer simulation study in ER-positive patients

 

Validation database

Simulation (mean±s.d.)

Initial imaging tests

 

116

104.0±6.5

BS and X-bone

53

52.2±3.8

MRI bone

8

15.3±2.2

FDG-PET/CT

3

1.2±0.3

X-ray lung

31

16.9±0.8

CT lung/liver

7

2.0±0.4

Ultrasound liver

7

7.0±0.3

MRI liver

0

0.2±0.1

MRI brain

7

9.2±2.5

FES-PET/CT

0

0.0±0.0

Staging tests

 

13

17.9±1.3

CT lung+CT liver

5

11.3±1.0

BS+CT lung+CT liver

8

6.6±0.9

Biopsy tests

 

18

20.3±1.5

Bone

6

7.4±1.0

Lung

10

5.6±0.5

Liver

0

3.3±0.2

Brain

2

4.0±1.0

MBCs found

 

14

10.2±1.0

Bone

8

3.7±0.6

Lung

3

2.7±0.3

Liver

2

2.6±0.2

Brain

1

1.2±0.3

  1. Abbreviations: BS, bone scan; CT=computed tomography; ER=oestrogen receptor; FDG=2-[18F]fluoro-2-deoxy-D-glucose; FES=16α-[18F]fluoro-17β-oestradiol; MBC=metastatic breast cancer; MBCSIM, metastatic breast cancer simulation; MRI=magnetic resonance imaging; PET=positron emission tomography.