Figure 1

Metastatic melanoma derivatives differ in lung colonisation ability independent of growth rate. (A) Representative images of lung colonisation at 4 weeks following tail vein injection of P2M5B (left) and P2M3C (right) tumour cells into C57BL/6 mice. (B) Quantification of surface lung colonies at 2, 4 and 6 weeks after tail vein injection of P2M3C and P2M5B cells. All C57BL/6 mice injected with P2M3C cells had died by 6 weeks because of tumour burden. (C) Tumour volume of P2M3C and P2M5B cells established as hind limb tumours in C57BL/6 mice. (D) Cell growth of P2M3C and P2M5B in tissue culture. Data represent mean±s.e.m. (n=3). *P⩽0.05.