Figure 4
From: Oncogenic CXCL10 signalling drives metastasis development and poor clinical outcome
The CXCL10 mediates cell growth and motility. The P2M3C and P2M5B cell growth in tissue culture (A) and as hind limb tumours in C57BL/6 mice (B) after transfection with shRNA targeting CXCL10 (KD #1 and KD #2) or a nontargeting control. The P2M3C and P2M5B cell migration (C), invasion (C) and adhesion (D) after shRNA-mediated suppression of CXCL10 as compared with a nontargeting control. Data represent mean±s.e.m. (n=3). *P⩽0.05. **P⩽0.001. NS indicates no significant difference.
