Table 1 Downregulated miRNAs in CRPC

From: MicroRNA expression signature of castration-resistant prostate cancer: the microRNA-221/222 cluster functions as a tumour suppressor and disease progression marker

miRNA

Log2 ratio (CRPC/non-PCa)

non-PCa

CRPC

P -value

hsa-miR-205

−11.34

0.00318

1.228E-06

0.0401

hsa-miR-378

−11.15

0.00336

1.479E-06

0.0485

hsa-miR-222

−8.40

0.11068

0.0003286

0.0161

hsa-miR-143

−8.34

0.05562

0.0001715

0.0465

hsa-miR-133a

−7.70

0.01215

5.847E-05

0.0203

hsa-miR-23b

−6.50

0.00103

1.138E-05

0.0276

hsa-miR-345

−6.45

0.00266

3.035E-05

0.0264

hsa-miR-150

−6.25

0.00945

0.0001244

0.0084

hsa-miR-139-5p

−6.22

0.00299

4.018E-05

0.0075

hsa-miR-221

−6.21

0.00208

2.822E-05

0.0355

hsa-miR-484

−5.68

0.01537

0.0003003

0.0144

hsa-miR-29c

−5.55

0.01459

0.0003123

0.0447

hsa-miR-28-3p

−5.44

0.00672

0.0001547

0.0262

hsa-miR-27b

−5.28

0.00134

3.444E-05

0.0362

hsa-miR-320

−5.26

0.01826

0.0004779

0.0382

hsa-miR-30a*

−5.21

0.00730

0.000197

0.0048

hsa-miR-532-3p

−5.21

0.00113

3.05E-05

0.0415

hsa-miR-574-3p

−5.15

0.02286

0.0006437

0.0048

hsa-miR-30e*

−5.13

0.00553

0.0001576

0.0105

hsa-miR-24

−5.06

0.14362

0.0043124

0.0215

hsa-miR-196b

−5.01

0.00183

5.666E-05

0.0023

hsa-miR-199a-3p

−4.50

0.01030

0.0004562

0.0434

hsa-miR-218

−4.43

0.00137

6.354E-05

0.0233

hsa-miR-27a

−4.31

0.00235

0.0001182

0.0426

hsa-miR-152

−4.25

0.00175

9.14E-05

0.0341

hsa-miR-660

−3.96

0.00165

0.0001059

0.0396

hsa-miR-126*

−3.61

0.00169

0.0001386

0.0191

hsa-miR-146a

−3.55

0.00718

0.0006132

0.0099

hsa-miR-20b

−3.52

0.00430

0.0003738

0.0333

hsa-miR-193b

−3.38

0.00966

0.0009259

0.0213

hsa-miR-106a

−2.93

0.03526

0.00462

0.0359

hsa-miR-125a-5p

−2.86

0.00179

0.0002467

0.0062

hsa-miR-149

−2.81

0.00538

0.000767

0.0211

hsa-miR-17

−2.77

0.02746

0.0040348

0.0460

hsa-miR-223

−2.66

0.01701

0.0026952

0.0189

hsa-miR-454

−2.46

0.00136

0.0002463

0.0077

hsa-miR-186

−2.46

0.00464

0.0008433

0.0093

hsa-miR-151-3p

−2.34

0.00238

0.0004702

0.0353

hsa-miR-16

−2.07

0.05451

0.0129807

0.0193

hsa-miR-342-3p

−2.04

0.00623

0.0015125

0.0207

hsa-miR-200c

−1.58

0.03969

0.0132931

0.0324

hsa-miR-126

−1.22

0.04305

0.0184953

0.0434

  1. Abbreviations: CRPC=castration-resistant prostate cancer; miRNA=microRNA; PCa=prostate cancer.
Back to article page