Table 1 TERT promoter mutations in phyllodes tumors and fibroadenomas of the breast

From: TERT promoter mutations are frequent and show association with MED12 mutations in phyllodes tumors of the breast

Histology

Number of cases

Total mutated

Nucleotide change

Cases mutated

Phyllodes tumor

46

30 (65%)

  

 Benign

18

9 (50%)

c.-146C>T

3

   

c.-124C>T

5

   

c.-124C>A

1

 Borderline

15

13 (87%)

c.-124C>T

13

 Malignant

13

8 (62%)

c.-146C>T

1

   

c.-124C>T

7

Fibroadenoma

58

4 (7%)

  

 Intracanalicular

32

2 (6%)

c.-124C>T

2

 Pericanalicular

20

2 (10%)

c.-124C>T

2

 Complex

6

0