Table 2 Impact of comorbidity burden on stage of disease at diagnosis (adjusted odds ratios (OR) from multinomial logistic regression models), for the total cohort and by cancer group

	Odds ratio for stage at diagnosis (OR, 95% CI)
C3 Index category	Local	Regional	Distant	Unknown
Total cohort ^a
0	Ref	Ref	Ref	Ref
1	Ref	0.92 (0.81–1.05)	1.09 (0.93–1.29)	0.91 (0.78–1.08)
2	Ref	1.01 (0.86–1.18)	1.29 (1.06–1.57)	1.1 (0.91–1.33)
3	Ref	1.09 (0.95–1.26)	1.49 (1.26–1.77)	1.85 (1.59–2.16)
Breast ^b
0	Ref	Ref	Ref	Ref
1	Ref	0.96 (0.77–1.2)	1.96 (1.22–3.13)	0.81 (0.56–1.19)
2	Ref	0.95 (0.71–1.28)	2.3 (1.31–4.02)	1.62 (1.12–2.34)
3	Ref	1.45 (1.09–1.91)	3.86 (2.36–6.3)	2.96 (2.17–4.05)
Colorectal ^b
0	Ref	Ref	Ref	Ref
1	Ref	1.03 (0.84–1.25)	1.25 (0.98–1.6)	0.87 (0.66–1.15)
2	Ref	1.12 (0.89–1.42)	1.46 (1.1–1.95)	1.08 (0.78–1.48)
3	Ref	0.93 (0.76–1.13)	1.25 (0.98–1.6)	1.87 (1.47–2.38)
Gynaecological ^b
0	Ref	Ref	Ref	Ref
1	Ref	0.8 (0.5–1.3)	1.01 (0.6–1.7)	1.11 (0.55–2.23)
2	Ref	0.79 (0.43–1.46)	0.65 (0.33–1.27)	1.5 (0.69–3.29)
3	Ref	1.28 (0.72–2.25)	1.74 (0.92–3.28)	4.92 (2.72–8.91)
Upper GI ^b
0	Ref	Ref	Ref	Ref
1	Ref	0.88 (0.41–1.87)	0.6 (0.3–1.17)	0.67 (0.37–1.24)
2	Ref	0.66 (0.27–1.62)	0.83 (0.38–1.77)	0.78 (0.39–1.58)
3	Ref	1.67 (0.73–3.86)	1.91 (0.89–4.1)	2.42 (1.17–5.01)
Urological ^b
0	Ref	Ref	Ref	Ref
1	Ref	0.65 (0.39–1.11)	0.92 (0.58–1.49)	0.86 (0.52–1.43)
2	Ref	0.98 (0.54–1.75)	0.89 (0.5–1.57)	0.88 (0.49–1.61)
3	Ref	1.04 (0.62–1.76)	1.21 (0.75–1.96)	1.55 (0.95–2.53)

Abbreviations: CI=confidence interval; GI=gastrointestinal; Ref=reference group.
^aAdjusted for age, sex (except for breast and gynaecological cancers), cancer group (e.g., colorectal), ethnicity (Māori/non-Māori) and deprivation (New Zealand Deprivation Index (NZDep) decile).
^bAdjusted for age, sex (except for breast and gynaecological cancers), cancer site (except breast; e.g., colon used as reference for colorectal model), ethnicity (Māori/non-Māori) and deprivation (NZDep decile).

Search