Figure 4 | British Journal of Cancer

Figure 4

From: Overall survival benefits of first-line EGFR tyrosine kinase inhibitors in EGFR-mutated non-small-cell lung cancers: a systematic review and meta-analysis

Figure 4

Progression-free survival analysis in L858R tumours. (A) PFS analysis in L858R tumours receiving reversible and irreversible TKIs. Pooled analysis showed significant PFS benefit only with reversible TKIs. (B) PFS analysis in L858R tumours receiving cisplatin- and carboplatin-based chemotherapy. Pooled analysis showed significant PFS benefit towards TKI treatment in both cisplatin- and carboplatin-based chemotherapy. Squares indicate study-specific HRs (size of the square reflects the study-specific statistical weight); horizontal lines indicate 95% CI; diamond indicates the summary HR estimate with its 95% CI.

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