Figure 1
From: FAT4 functions as a tumour suppressor in gastric cancer by modulating Wnt/β-catenin signalling
FAT4 expression in gastric cancer tissues. (A) FAT4 mRNA expression levels in 30 paired gastric cancer tissues and adjacent non-cancerous tissues expressed as relative expression normalised to the expression of β-actin and calculated by the 2−ΔΔct method. *P<0.05 by Mann–Whitney U-test. (B) FAT4 protein expression in representative samples of gastric cancer tissues (T) and paired adjacent non-cancerous tissues (N). *P<0.05 by Student’s t-test. (C) Immunohistochemical staining of FAT4 in gastric cancer tissues. Original magnification, × 200, × 400; bar=100 μm. (D) Kaplan–Meier survival analysis according to FAT4 expression in gastric cancer patients (N=160). The P-values from log-rank tests comparing the two KM curves are shown.
