Table 2 Comparison of molecular alterations between Group GC and the controls

From: Effects of Helicobacter pylori eradication on the development of metachronous gastric cancer after endoscopic treatment: analysis of molecular alterations by a randomised controlled trial

 

Group GC

 

Control (%)

     

P

Molecular markers

H. pylori +ve (%)

H. pylori −ve (%)

P

 

vs H. pylori +ve

vs H. pylori −ve

MSI

45 (44.1)

13 (44.8)

0.95

3 (13.6)

0.008a

0.02a

hMLH1

30 (29.4)

7 (24.1)

0.58

6 (27.3)

0.84

0.80

CDKN2A

1 (1.0)

0 (0)

>0.99a

0 (0)

>0.99a

>0.99a

APC

9 (8.8)

3 (10.3)

0.73a

5 (22.7)

0.13a

0.27a

mAb Das-1 reactivity

59 (57.8)

18 (62.1)

0.68

8 (36.4)

0.07

0.07

  1. Abbreviations: APC=adenomatous polyposis coli; GC=gastric cancer; mAb=monoclonal antibody; MSI=microsatellite instability.
  2. aFisher’s exact test.
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