Table 1 Cohort characteristics
Cohort characteristics | Total n =418 |
|---|---|
Patient characteristics | |
Age in years, median (IQR) | 70 (61–76) |
Female sex, n (%) | 96 (23.0) |
Heavy smoking (⩾30pack-years), n (%) | 133 (32) |
BMI (kg/m2), median (IQR) | 27 (24–30) |
Charlson co-morbidity index, median (IQR) | 1 (0–2) |
Disease characteristics | |
Hydronephrosis, n (%) | 117 (28) |
Concurrent CIS, n (%) | 188 (45) |
T-stage, n (%) | |
pT0 | 25 (6) |
pTa/Tis/T1/T2 | 202 (48) |
pT3/T4 | 191 (46) |
N-stage, n (%) | |
pN0 | 282 (68) |
pN+ | 115 (27) |
pNx | 21 (5) |
Lymphovascular invasion, n (%) | 141 (34) |
Positive surgical margina, n (%) | 33 (8) |
Other treatment characteristics | |
Year of surgery, n (%) | |
1992–2005 | 208 (50) |
2006–2012 | 210 (50) |
Continent diversion, n (%) | 89 (21) |
Node total, median (IQR) | 12 (7–19) |
Neo-adjuvant chemotherapy, n (%) | 28 (7) |
Adjuvant chemotherapy, n (%) | 87 (20) |
Salvage chemotherapy, n (%) | 54 (13) |
CBC-based parameters | |
Haemoglobin (g/dl), median (IQR) | 13.2 (11.6–14.5) |
WBC (× 109/l), median (IQR) | 7.6 (6.0–9.1) |
Neutrophils (× 109/l), median (IQR) | 4.8 (3.8–6.5) |
Monocytes (× 109/l), median (IQR) | 0.6 (0.5–0.7) |
Lymphocytes (× 109/l), median (IQR) | 1.7 (1.3–2.1) |
Platelets (× 109/l), median (IQR) | 253 (204–303) |
NLR, median (IQR) | 2.9 (2.1–4.3) |
MLR, median (IQR) | 0.36 (0.26–0.50) |
LMR, median (IQR) | 2.8 (2.0–3.8) |
PLR, median (IQR) | 150 (103–202) |
