Table 4 Multivariate analysis for overall survival including lymphocytic reaction at invasive margin
Covariate | N | P -value | HR | 95% CI |
|---|---|---|---|---|
NLR | ||||
<5 | 260 | — | 1.00 | — |
⩾5 | 84 | 0.002 | 1.712 | 1.227–2.389 |
Age (years) | ||||
⩽70 | 123 | — | 1.00 | — |
>70 | 221 | <0.001 | 3.008 | 2.067–4.376 |
EMVI | ||||
Yes | 138 | — | 1.00 | — |
No | 212 | 0.144 | 1.294 | 0.916–1.827 |
Dukes’ stage | ||||
A | 36 | — | 1.00 | — |
B | 152 | 0.635 | 0.857 | 0.454–1.619 |
C | 119 | 0.089 | 1.763 | 0.916–3.392 |
D | 37 | <0.001 | 5.649 | 2.731–11.683 |
Lymphocytic reaction (grade) | ||||
None/mild | 237 | — | 1.00 | — |
Moderate/severe | 107 | 0.135 | 0.757 | 0.526–1.090 |
