Table 5 Multivariate analysis for disease-free survival including lymphocytic reaction at invasive margin

From: Systemic neutrophil-to-lymphocyte ratio in colorectal cancer: the relationship to patient survival, tumour biology and local lymphocytic response to tumour

Covariate

N

P -value

HR

95% CI

NLR

<5

234

1.00

5

65

0.007

2.185

1.233–3.871

Complete resection

Yes

106

1.00

No

193

0.355

0.727

0.370–1.429

EMVI

Yes

270

1.00

No

29

0.007

2.187

1.234–3.874

Dukes’ stage

A

36

1.00

B

150

0.797

0.864

0.284–2.631

C

113

0.084

2.660

0.877–8.064

Lymphocytic reaction (grade)

None/mild

201

1.00

Moderate/severe

98

0.253

1.420

0.778–2.589

  1. Abbreviations: EMVI=extramural vascular invasion; HR=hazard ratio; NLR=neutrophil-to-lymphocyte ratio.