Table 1 Univariate and multivariate survival analyses in TNBC patients (n=56)

From: Cancer-associated oxidoreductase ERO1-α drives the production of VEGF via oxidative protein folding and regulating the mRNA level

Items

Contents

HR

95% CI

P- value

Univariate survival analysis

Age

<60 years

1

  
 

60–69 years

2.17

0.61, 7.70

0.23

 

70 years

2.41

0.60, 9.73

0.218

 

Total

  

0.157

Basal

Non-basal

1

 

 

Basal

5.92

0.77, 45.63

0.088

 

Total

  

Stage

I or II

1

 

 

III

3.66

0.94, 14.17

0.061

 

IV

10.09

2.55, 39.93

0.001

 

Total

  

<0.001

ALDH1

(−)

1

 

 

(1+)

2.02

0.37, 11.02

0.418

 

(2+)

3.6

0.51, 25.64

0.201

 

(3+)

2.08

0.35, 12.45

0.423

 

Total

  

0.386

ERO1-α

(−) or (1+)

1

 

 

(2+)

4.95

0.91, 27.06

0.065

 

(3+)

5.99

1.09, 32.76

0.039

 

Total

  

0.029

Multivariate survival analysis

Stage

I or II

1

  
 

III

1.79

0.35, 9.26

0.489

 

IV

14.92

2.20, 101.09

0.006

 

Total

  

0.011

ERO1-α

(−) or (1+)

1

 

 

(2+)

6.69

1.01, 44.15

0.048

 

(3+)

5.99

1.05, 36.23

0.044

 

Total

  

0.041

  1. Abbreviations: ALDH1=aldehyde dehydrogenase-1; CI=confidence interval; ERO1-α=endoplasmic reticulum disulfide oxidase 1-α; HR=hazard ratio.