Figure 5 | British Journal of Cancer

Figure 5

From: Loss of N-acetylgalactosaminyltransferase 3 in poorly differentiated pancreatic cancer: augmented aggressiveness and aberrant ErbB family glycosylation

Figure 5

Altered morphology and increased adhesion of GALNT3 knockdown cells to endothelium monolayer. (A) Epithelial–mesenchymal transition-like morphological changes in GALNT3 knockdown CD18/HPAF and BxPC3 PDAC cells. (B) Increased expression of metastatic SLex carbohydrate epitope in GALNT3 knockdown PDAC cells. (C) Bar graphs represent significant increase in percentage adhesion of GALNT3 knockdown cells to endothelial monolayer (**P<0.001). Representative immunofluorescent images showing increased adhesion of GALNT3 knockdown cells to endothelium monolayer as compared with scrambled control cells (Green-cancer cells).

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