Table 1 Baseline characteristics of the study cohort

From: Risk factors of proteinuria in renal cell carcinoma patients treated with VEGF inhibitors: a secondary analysis of pooled clinical trial data

Variable

Mean±s.d., or n (%)

Pre-existing proteinuria

221 (18)

Age (years)

60.1±10.8

Male sex

1005 (72)

Ethnicity

 

 White

952 (68)

 Asiana

414 (30)

 Other

26 (2)

SBP (mm Hg)

126±13

DBP (mm Hg)

75±8.9

Heart rate

78±12

BSA (m2)

1.91±0.27

Diabetes

178 (13)

eGFR (ml min−1)

72±26

Prior nephrectomy

1179 (85)

VEGF inhibitor allocated

 

 Pazopanib

844 (61)

 Sunitinib

548 (39)

Use of ASI

350 (26)

 ACEI

223 (16)

 ARB

135 (10)

Use of other AHD

482 (36)

 CCB

270 (20)

 Beta blocker

234 (17)

 Thiazide diuretic

161 (12)

Use of nephrotoxic drug

342 (25)

 NSAID

307 (23)

 Bisphosphonate

61 (4)

  1. Abbreviations: ACEI=angiotensin converting enzyme inhibitor; AHD=antihypertensive drug; ARB=angiotensin receptor blocker; ASI=angiotensin system inhibitor; BSA=body surface area; CCB=calcium channel blocker; DBP=diastolic blood pressure; eGFR=estimated glomerular filtration rate; NSAID=non-steroidal anti-inflammatory drug; SBP=systolic blood pressure; VEGF: vascular endothelial growth factor.
  2. aPredominantly East Asian or Japanese heritage.
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