Table 1 MR results showing the relationship between CRC risk, and adult BMI and adult WHR in the meta-analysis with published data

From: Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer

 

BMI

WHR

Sex

OR (95% CI)

P value

OR (95% CI)

P value

All

1.26 (1.10–1.44)

7.73 × 10−4

1.40 (1.14–1.72)

1.22 × 10−3

Male

1.12 (0.92–1.38)

0.262

1.63 (1.20–2.22)

1.98 × 10−3

Female

1.43 (1.17–1.74)

4.25 × 10−4

1.22 (0.91–1.63)

0.178

  1. Abbreviations: MR=Mendelian randomisation; CRC=colorectal cancer; BMI=body mass index; WHR=waist-hip ratio; OR=odds ratio; CI=confidence interval.
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