Table 2 The area under the receiver operator curve for the discrimination between benign and malignant lesions for ADNEX with and without CA125 according to type of centre and sonographer

From: Evaluating the risk of ovarian cancer before surgery using the ADNEX model: a multicentre external validation study

 

ADNEX with CA125

ADNEX without CA125

Subgroup

AUC

95% CI

AUC

95% CI

All patients

0.937

0.915–0.954

0.925

0.902–0.943

Centre

    

 QCCH

0.942

0.913–0.962

0.931

0.900–0.953

 PAH

0.900

0.841–0.938

0.889

0.828–0.930

 GNH

0.990

0.959–0.998

0.983

0.950–0.995

Operator profession

    

 MD

0.939

0.917–0.956

0.924

0.900–0.943

 Sonographer

0.912

0.809–0.962

0.916

0.818–0.964

Menopausal status

    

 Premenopausal

0.939

0.901–0.963

0.935

0.901–0.958

 Postmenopausal

0.899

0.855–0.931

0.873

0.824–0.910

  1. Abbreviations: ADNEX=The Assessment of Different NEoplasias in the adneXa; AUC=area under the receiver operating curve; CA125=cancer antigen 125; CI=confidence interval; MD=medically qualified doctor; QCCH=Queen Charlotte’s and Chelsea Hospital; PAH=Princess Anne Hospital; GNH=Garibaldi Nesima Hospital.