Table 2 Multivariate backward Cox-regression analysis for disease-free survival after 5 years of KCNQ1 and clinicopathological parameters that were retained in the model

From: Loss of KCNQ1 expression in stage II and stage III colon cancer is a strong prognostic factor for disease recurrence

Parameters

HR

95%-CI

P -value

Isolated tumour deposits

1.594

0.98–2.59

0.06

Nodal stage

1.683

1.30–2.18

0.0001

Angio-invasion

2.062

1.32–3.22

0.001

MSI status

0.589

0.34–1.03

0.06

Low KCNQ1-expression

3.752

2.50–5.64

<0.0001

  1. Abbreviations: CI=confidence interval; HR=hazards ratio; MSI=microsatellite instability.