Table 4 Risk of toxicity during ipilimumab treatment in relation to BMI, sarcopenia and low MA determined by multiple logistic regressions

From: The impact of body composition parameters on ipilimumab toxicity and survival in patients with metastatic melanoma

  

Model 1 a

Model 2 a

 

High-grade AE

High-grade irAE

 

n

OR

95% CI

P-value

OR

95% CI

P-value

BMI (>25 kg m−2)

59

4.01

1.03–15.69

0.046

2.46

0.67–9.02

0.173

Sarcopenia

20

5.34

1.15–24.88

0.033

2.17

0.58–8.11

0.248

Low MA

24

5.23

1.41–19.30

0.013

3.57

1.09–11.77

0.036

  1. Abbreviations: AE=adverse event; BMI=body mass index; irAE=immune-related adverse event; MA=Muscle Attenuation.
  2. aAdjusted for gender and age (>65 vs <65 years) as potential confounders.
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