Figure 1

Location and expression levels of clustered miR-224/452 and its associations with CRPC progression-free interval. (A) Location of the miR-224/452 cluster in the human genome. (B) Expression levels of miR-452 in PCa clinical specimens and cell lines. RNU48 was used for normalisation. (C) Expression levels of miR-224 in PCa clinical specimens. RNU48 was used for normalisation. (D) Correlations among the relative expression levels of miR-224 and miR-452. (E) Kaplan–Meier analysis for expression level of miR-452 and CRPC-free rate. (F) Kaplan–Meier analysis for expression level of miR-224 and CRPC-free rate.