Table 1 The modified geriatric assessmenta
From: Geriatric assessment is superior to oncologists’ clinical judgement in identifying frailty
Domain | Scale | Range | Rated by | Cutoff value for frailty | Rationale for cutoff values |
|---|---|---|---|---|---|
Activities of daily living | EORTC QLQ-C30 Q5b | Patient | If reported yes a little/quite a bit/very much on the question ‘Do you need help with eating, dressing, washing yourself or using the toilet’ | ADL-deficiencies previously used in frailty classifications of cancer patients (Balducci and Extermann, 2000) | |
Comorbidity | OARSc | 0–15 (Higher score indicates more comorbidities) | Patient | >3 points | Threshold for shorter survival in previous study of cancer patients (Klepin et al, 2014) |
Medications, polypharmacy | ATCd | 0–13 | Nurse/ MD | >7 regular medications (ointments & common vitamins excluded) | Previously used in frailty classifications of cancer patients (Ommundsen et al, 2014) |
Physical function | TUGe | Nurse | >14 seconds | Similar cut-offs (⩾14/>14.5) used to identify GA deficits in cancer trials (Owusu et al, 2011; Jolly et al, 2015; Williams et al, 2015) | |
Cognitive function | MMSEf | 0–30 (Higher score indicates better function) | Nurse | <24 points | Previously used in frailty classifications of cancer patients (Ommundsen et al, 2014) |
Depressive symptoms | GDS-15g | 0–15 (Higher score indicates more symptoms) | Patient | ⩾7 points | Chosen to ensure high specificity (Friedman et al, 2005; Cullum et al; 2006) |
Nutritional status | PG-SGAh | Nurse/Patient | Considered severely malnourished by nurse or self-reported weight loss ⩾10% the last 6 months. | Weight loss ⩾ 10% the last six months is generally considered as an indicator of severe malnutrition (Nitenberg and Raynard, 2000) | |
Falls | Nurse | Patient reports ⩾2 falls the last 6 months | Previously used to identify GA deficits in cancer trials (Owusu et al, 2011; Jolly et al, 2015) |