Table 1 The modified geriatric assessmenta

From: Geriatric assessment is superior to oncologists’ clinical judgement in identifying frailty

Domain

Scale

Range

Rated by

Cutoff value for frailty

Rationale for cutoff values

Activities of daily living

EORTC QLQ-C30 Q5b

 

Patient

If reported yes a little/quite a bit/very much on the question ‘Do you need help with eating, dressing, washing yourself or using the toilet’

ADL-deficiencies previously used in frailty classifications of cancer patients (Balducci and Extermann, 2000)

Comorbidity

OARSc

0–15 (Higher score indicates more comorbidities)

Patient

>3 points

Threshold for shorter survival in previous study of cancer patients (Klepin et al, 2014)

Medications, polypharmacy

ATCd

0–13

Nurse/ MD

>7 regular medications (ointments & common vitamins excluded)

Previously used in frailty classifications of cancer patients (Ommundsen et al, 2014)

Physical function

TUGe

 

Nurse

>14 seconds

Similar cut-offs (14/>14.5) used to identify GA deficits in cancer trials (Owusu et al, 2011; Jolly et al, 2015; Williams et al, 2015)

Cognitive function

MMSEf

0–30 (Higher score indicates better function)

Nurse

<24 points

Previously used in frailty classifications of cancer patients (Ommundsen et al, 2014)

Depressive symptoms

GDS-15g

0–15 (Higher score indicates more symptoms)

Patient

7 points

Chosen to ensure high specificity (Friedman et al, 2005; Cullum et al; 2006)

Nutritional status

PG-SGAh

 

Nurse/Patient

Considered severely malnourished by nurse or self-reported weight loss 10% the last 6 months.

Weight loss 10% the last six months is generally considered as an indicator of severe malnutrition (Nitenberg and Raynard, 2000)

Falls

  

Nurse

Patient reports 2 falls the last 6 months

Previously used to identify GA deficits in cancer trials (Owusu et al, 2011; Jolly et al, 2015)

  1. aPatients were classified as mGA-frail if having 1 of the criteria listed in the table.
  2. bThe European Organisation for Research and Treatment of Cancer Quality of Life Core Questionnaire.
  3. cThe Physical Health Section of the Older Americans’ Resources and Services Questionnaire.
  4. dAnatomical Therapeutic Chemical Classification System.
  5. eTimed up and Go test.
  6. fNorwegian Revised Mini Mental State Examination.
  7. gGeriatric depression scale.
  8. hPatient-generated Subjective Global Assessment.