Table 3 Chromosomal distribution of genes related to CNA and validation in TCGA data

From: Comprehensive analysis of copy number aberrations in microsatellite stable colon cancer in view of stromal component

Chr

Number of genes

Genes in CNA region

Significant genes a

Validation in TCGA data

Validation in MSS and stage II in TCGA data

1

1542

44 (2.85 %)

2

1

0

2

1013

23 (2.27 %)

1

0

0

3

847

49 (5.8 %)

3

0

0

4

606

20 (3.3 %)

1

0

0

5

680

64 (9.4 %)

12

0

0

6

812

105 (13 %)

30

1

0

7

733

150 (20.5 %)

18

0

10

8

528

518 (98.1 %)

282

220

134

9

599

27 (4.5 %)

4

3

1

10

579

35 (6.04 %)

3

0

0

11

896

36 (4.02 %)

1

0

0

12

779

39 (5 %)

17

5

5

13

268

268 (100 %)

115

91

74

14

496

17 (3.43 %)

0

0

0

15

487

17 (3.49 %)

1

0

0

16

679

32 (4.71 %)

2

1

0

17

921

142 (15.42 %)

36

5

1

18

210

97 (46.19 %)

35

5

2

19

1033

30 (2.9 %)

0

0

0

20

416

412 (99.04 %)

221

164

135

21

156

17 (10.9 %)

0

0

0

22

374

26 (6.9 %)

1

0

1

Total

14654

2168 (14.8 %)

785

488

363

  1. Abbreviations: CNA=copy number aberration; FDR=false discovery rate; MSS=microsatellite stable; TCGA=The Cancer Genome Atlas.
  2. aFDR was used to identify significant associations.