Table 3 Chromosomal distribution of genes related to CNA and validation in TCGA data
Chr | Number of genes | Genes in CNA region | Significant genes a | Validation in TCGA data | Validation in MSS and stage II in TCGA data |
---|---|---|---|---|---|
1 | 1542 | 44 (2.85 %) | 2 | 1 | 0 |
2 | 1013 | 23 (2.27 %) | 1 | 0 | 0 |
3 | 847 | 49 (5.8 %) | 3 | 0 | 0 |
4 | 606 | 20 (3.3 %) | 1 | 0 | 0 |
5 | 680 | 64 (9.4 %) | 12 | 0 | 0 |
6 | 812 | 105 (13 %) | 30 | 1 | 0 |
7 | 733 | 150 (20.5 %) | 18 | 0 | 10 |
8 | 528 | 518 (98.1 %) | 282 | 220 | 134 |
9 | 599 | 27 (4.5 %) | 4 | 3 | 1 |
10 | 579 | 35 (6.04 %) | 3 | 0 | 0 |
11 | 896 | 36 (4.02 %) | 1 | 0 | 0 |
12 | 779 | 39 (5 %) | 17 | 5 | 5 |
13 | 268 | 268 (100 %) | 115 | 91 | 74 |
14 | 496 | 17 (3.43 %) | 0 | 0 | 0 |
15 | 487 | 17 (3.49 %) | 1 | 0 | 0 |
16 | 679 | 32 (4.71 %) | 2 | 1 | 0 |
17 | 921 | 142 (15.42 %) | 36 | 5 | 1 |
18 | 210 | 97 (46.19 %) | 35 | 5 | 2 |
19 | 1033 | 30 (2.9 %) | 0 | 0 | 0 |
20 | 416 | 412 (99.04 %) | 221 | 164 | 135 |
21 | 156 | 17 (10.9 %) | 0 | 0 | 0 |
22 | 374 | 26 (6.9 %) | 1 | 0 | 1 |
Total | 14654 | 2168 (14.8 %) | 785 | 488 | 363 |