Table 1 Distribution of participant characteristics (weighted by person-years) across the entire follow-up time, in quintiles of the empirical dietary inflammatory pattern scores in the NHS (1984–2012) and the NHS-II (1991–2013)a,b,c

From: The inflammatory potential of diet and ovarian cancer risk: results from two prospective cohort studies

 

Nurses’ Health Study (NHS)

Nurses’ Health Study II (NHS-II)

Characteristic

Q1

Q3

Q5

Q1

Q3

Q5

Average person-years

390 941

319 212

234 015

271 982

344 572

431 470

Age, year

62.1±9.5d

63.8±10.0

61.6±9.8

48.6±7.0

47.1±7.2

45.7±7.2

History of tubal ligation, %

21.0

20.0

21.9

22.8

23.9

25.7

History of hysterectomy, %

19.1

22.4

23.3

7.6

8.6

9.9

Family history of breast or ovarian cancer, %

27.4

30.5

25.9

13.8

12.4

11.3

Current smoker, %

17.2

11.4

13.5

9.8

8.3

10.9

Parous, %

94.4

94.8

94.4

79.6

81.7

79.7

No. of children in parous womene

3

3

3

2

2

2

Duration of breastfeeding in parous women, month

6.7±10.4

6.2±10.2

5.6±9.8

16.5±14.4

15.2±14.2

12.5±13.0

Oral contraceptive use, ever, %

52.7

49.4

52.7

86.6

85.8

84.2

Duration of oral contraceptive use in ever users, year

4.1±3.9

4.0±3.8

4.0±3.9

5.4±4.9

5.5±4.9

5.5±4.8

Postmenopausal, %

81.6

84.2

78.6

31.2

23.9

18.4

Estrogen-only HT usef, %

17.2

19.0

17.2

9.8

10.1

10.0

Duration of estrogen-only HT useg, year

7.2±6.3

8.0±7.0

7.5±6.6

3.3±3.5

3.9±3.8

4.2±4.1

Estrogen-progestin HT usef, %

32.0

28.7

23.9

34.5

34.2

30.8

Duration of estrogen-progestin HT useg, year

5.8±4.1

5.7±4.1

5.2±3.7

3.3±2.9

3.3±2.9

3.1±2.8

Alcohol intake, g d−1

9.7±12.6

4.3±7.2

3.4±6.7

9.6±12.5

4.2±6.0

2.9±4.6

Total energy intake, Kcal d−1

1780±533

1668±527

1814±582

1947±574

1756±550

1857±601

Used 1 of 15 supplementsh, %

76.2

74.9

67.9

72.7

69.9

63.0

Physical activity, MET-hour per week

20.1±23.7

17.4±20.9

15.5±19.2

25.9±28.7

21.2±24.2

18.9±23.2

Waist-to-hip ratio (WHR)

0.81±0.15

0.82±0.11

0.84±0.11

0.80±0.07

0.81±0.07

0.82±0.08

WHR 0.80, %

45.7

53.6

62.0

48.3

52.3

61.7

Body mass index, kg m−2

24.9±4.4

26.3±5.1

28.4±6.2

25.3±5.2

26.2±5.8

28.3±7.2

Overweight/obese, 25 kg m−2, %

41.6

54.4

67.4

41.6

47.8

60.6

  1. aEDIP=empirical dietary inflammatory pattern score; HT=postmenopausal hormone therapy; NHS=Nurses’ Health Study; NHS-II=Nurses’ Health Study-II; Q=quintile.
  2. bWeighted by follow-up time (person-years) accrued by each participant.
  3. cEDIP scores were adjusted for energy intake using the residual method. In the EDIP quintiles, lower EDIP scores indicate anti-inflammatory diets and higher scores, pro-inflammatory diets.
  4. dMean±s.d. (all such values).
  5. eAverage rounded to the nearest whole number.
  6. fAmong postmenopausal women.
  7. gAmong postmenopausal women using HT.
  8. hThe 15 supplements included were: multivitamins, vitamin A, beta-carotene, vitamin C, vitamin D, vitamin E, vitamin B-complex, folic acid, niacin (when used separately from B-complex), calcium, iron, selenium, zinc, magnesium and fish oil.