Figure 4 | British Journal of Cancer

Figure 4

From: Interleukin-10-regulated tumour tolerance in non-small cell lung cancer

Figure 4

IL-10 and IL-10R directly correlated in NSCLC and in SCC, but not in ADC, IL-10R directly correlated with PDL1 and HIF1α. (A) Correlation of IL-10R mRNA level and IL-10 in ADC CTR (coincident pairs n=14) and TU (coincident pairs n=14) and between IL-10R and NSCLC CTR (coincident pairs n=21) and TU (coincident pairs n=22). (B) Correlation of IL-10R mRNA level and PDL1 in NSCLC. Coincident pairs ADC CTR n=13, coincident pairs ADC TU n=12, coincident pairs SCC CTR n=8, coincident pairs SCC TU n=9. (C) Correlation of HIF1-alpha mRNA level and IL-10R in SCC CTR (coincident pairs n=8) and NSCLC CTR (coincident pairs n=22). Bar chart is shown as mean values±s.e.m. using Student’s t-test *P<0.05, **P<0.01 and ***P<0.001.

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