Table 1 Clinical characteristics of the patient cohort

Sample ID	Histolo-gical classi-fication	Maximal tumour diameter (cm)	Grading	T	N	M	TNM stadium	Gender	Age	Average smoking (P/Y)
1-MP	SCC	1.3	G3	1b	0	0	IA	Male	80	40
2-MP	SCC	5.1	G3	1a	0	0	IA	Male	57	40
3-MP	ADC	5	G3	2a	0	0	IB	Male	79	60
4-MP	SCC	2	G3	1b	1	0	IIA	Female	53	25
5-MP	SCC	10.5	G2	3	0	0	IIB	Female	67	50
8-MP	SCC	5.5	G3	3	0	0	IIB	Male	66	30
9-MP	ADC	2.7	G2	1b	2	0	IIIA	Female	84	0
13-MP	SCC	3	G3	1b	0	0	IA	Male	69	50
14-MP	SCC	1.9	G2	1a	0	0	IA	Female	58	30
15-MP	ADC	2,5	G3	1b	0	0	IA	Male	63	100
16-MP	ADC	4.6	G3	3	0	0	II B	Female	70	15
17-MP	ADC	2.6	G2	2	0	0	IB	Male	74	70
19-MP	ADC	6.5	#	2b	0	0	IIA	Female	55	30
20-MP	ADC	2.8	G3	1b	0	0	IA	Male	65	60
21-MP	SCC	2.5	G1	1b	0	0	IA	Male	41	10
22-MP	ADC	7	G3	2b	1	0	IIB	Male	68	82
23-MP	ADC	4.5	G2	2a	0	0	IB	Male	73	75
26-MP	ADC	1.3	G3	1a	0	1	IV	Female	52	50
27-MP	ADC	1.4	G3	1a	0	0	IA	Female	70	50
28-MP	ADC	1.2	G3	1a	0	0	IA	Male	76	60
29-MP	SCC	3.7	G3	1b	0	0	IIB	Male	74	100
30-MP	SCC	1.8	G3	1a	0	0	IA	Female	70	30
32-MP	ADC	4.4	G3	2a	2	0	IIIA	Female	60	30
34-MP	ADC	1.8	G3	1	0	0	I A	Female	51	45
35-MP	ADC	3	G3	1b	0	0	IA	Female	72	0
36-MP	SCC	3.5	G3	2a	1	0	IB	Male	74	40
37-MP	SCC	3.3	G2	2a	1	0	IIA	Male	60	45
39-MP	ADC	6	G3	2b	0	0	IIA	Male	65	42
40-MP	ADC	1.8	G3	1a	1	0	IIA	Male	82	100
41-MP	SCC	1.3	G3	3	1	0	IIIA	Male	70	42
42-MP	SCC	1.5	G3	2b	1	0	IIB	Male	74	40
46-MP	SCC	9.5	G3	3	1	0	IIIA	Male	60	30
47-MP	SCC	6	G3	2b	0	0	IIA	Male	64	80
48-MP	SCC	5	G2	2b	0	0	IIA	Male	55	20

Abbreviations: ADC=adenocarcinoma; SCC=squamous cell carcinoma of the lung.
T-primary tumour: 0=no evidence of primary tumour; 1a=tumour 2 cm or less in greatest dimension; 1b=tumour more than 2 cm but not more than 3 cm in greatest dimension; 2a=tumour more than 3 cm but not more than 5 cm in greatest dimension; 2b=tumour more than 5 cm but not more than 7 cm in greatest dimension; 3=tumour more than 7 cm.
N-regional lymph nodes: 0=no regional lymph node metastasis; 1=metastasis in ipsilateral peribronchial and/or ipsilateral hilar lymph nodes and intrapulmonary nodes, including involvement by direct extension; 2=Metastasis in ipsilateral mediastinal and/or subcarinal lymph node(s).
M-distant metastasis: 0=no distant metastasis; 1=distant metastasis.
Histopathological grading: G1=well differentiated; G2=moderately differentiated; G3=poorly differentiated.
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