Figure 2

Kaplan-Meier curves for patients with high and low levels of metabolites and ratios. Recurrence-free proportions plotted against time to first report of recurrence for spermine (A), citrate (B), tChoCre/Spm (C), and tChoCre/Cit (D) dichotomised to above and below median concentrations. Mantel–Haenszel log-rank test was used to test for the null hypothesis of equal survival distributions. tChoCre/Cit, (total-choline+creatine)/citrate; tChoCre/Spm, (total-choline+creatine)/spermine.