Table 1 Demographic and clinical characteristics of the germ cell tumour probands

From: Family history of cancer in children and adolescents with germ cell tumours: a report from the Children’s Oncology Group

 

Male probands N a =340

Female Probands N a =330

Age at diagnosis

0–4

66 (19)

105 (32)

5–9

17 (5)

50 (15)

10–14

77 (23)

114 (35)

15–19

180 (53)

61 (19)

Tumour Histology

Germinoma

103 (30)

67 (20)

Teratoma

51 (15)

105 (32)

Yolk Sac Tumour (YST)

42 (12)

73 (22)

Mixed/Other

126 (37)

50 (15)

Teratoma and YST

6 (2)

27 (8)

Unknown

12 (4)

8 (2)

Tumour location

Ovary

—

177 (54)

Testis

136 (40)

—

Intracranial

133 (39)

52 (16)

Extragonadal

71 (21)

101 (31)

Cryptorchidism

Yes

16 (5)

N/A

Number relatives per family

Mean # (SD)

12.5 (4.5)

11.4 (3.9)

Relatives by type

Mothers

336

326

Fathers

322

303

Siblingsb

591

585

Grandparents

1241

1196

Aunts/unclesc

1754

1344

  1. aNumbers may not sum to total due to missing values.
  2. bIncludes full and half siblings.
  3. cDoes not include half-aunts and half-uncles.
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