Figure 6
From: Dual roles of tumour cells-derived matrix metalloproteinase 2 on brain tumour growth and invasion
MMP2 expression was associated with vascular function. (A) Representative images of ALTS1C1 and MMP2kd tumours stained with CD31 and NG2. Scale bar: 50 μm. (B) Quantification of the ratio of NG2 covered on the blood vessels at the indicated day after tumour implantation. (C) Representative images of blood perfusion and hypoxia in ALTS1C1 and MMP2kd tumours. CD31 and PIMO were stained to identify vessels and tumour hypoxia, respectively, and the blood perfusion was visualised using Hoechst33342. Scale bar: 200 μm. (D) Quantification of the blood perfusion (left panel) and hypoxia area (right panel) in tumours. *P<0.05, **P<0.01.
