Figure 4
From: Intracrine androgen biosynthesis in renal cell carcinoma
Physiologically significant androgens and androgen biosynthesis enzymes are detected in human female RCC tissues positive for AR.(A) RT-PCR confirmed the presence of the key enzymes required for the intratumoral androgen biosynthesis in human female RCC tissues. LNCaP, the human prostate cancer cell lines, was used as the positive control. (B) ELISA for T and DHT in human RCC tissues obtained from three males and females demonstrated androgen concentrations in the thousands nanogram per mg protein range.
