Table 4 Results in the adjuvant chemoradiotherapy treatment arms of selected studies on patients with gastric cancer undergoing surgery and D2 lymph node dissection

From: S-1 chemotherapy and intensity-modulated radiotherapy after D1/D2 lymph node dissection in patients with node-positive gastric cancer: a phase I/II study

Author (year)

Median no. of PLNs a /percentage of patients with stage III or IV (M0) a

Regimen/technique

End point

Shim, et al (2016)

5.5/63

S-1+45 Gy/AP-PA

3-year DFS 65.2%, OS 76.1%

Kim, et al (2012)

8/100

FL+45 Gy/AP-PA

5-year DFS 60.9%, OS 65.2%

Zhu, et al (2012)

NM/71.2

FL+45 Gy/IMRT

5-year DFS 45.2%, OS 48.4%

ARTIST (2012)

3/42.1

Capecitabine+45 Gy/AP-PA

3-year DFS 78.2%,

  1. Abbreviations: AP-PA=anterior–posterior parallel opposing fields; ARTIST=Adjuvant Chemoradiotherapy in Stomach Tumours; DFS=disease-free survival; FL=5-fluorouracil and leucovorin; IMRT=intensity-modulated radiotherapy; NM=not mentioned; OS=overall survival; PLNs=positive lymph nodes.
  2. aAmong patients treated with ACRT.