Figure 4
Effects of si-ITGA3 transfection on BC cell lines.(A) The expression of ITGA3 mRNA was significantly repressed in si-ITGA3 transfectants in comparison with that in mock or si-control transfectants. GUSB was used as an internal control. *P<0.0001. (B) The expression of ITGA3 protein was markedly repressed in si-ITGA3 transfectants in comparison with that in mock or si-control transfectants. β-Actin was used as a loading control. (C) Cell proliferation was determined by XTT assays. (D) Cell migration activity was determined using wound-healing assays. (E) Cell invasion activity was determined with Matrigel invasion assays. *P<0.0001.
