Figure 6
Analysis of the clinical BC specimens in TCGA data sets.(A) The expression level of ITGA3 mRNA was significantly upregulated in BC tissues compared with that in normal bladder tissues (P=0.0063). (B) Negative correlations between ITGA3 expression and miR-199a-1, miR-199a-2, and miR-199b expression in BC tissues (P=0.0099, R=−0.128; P=0.0189, R=−0.117; and P=0.033, R=−0.106, respectively). (C) Overall survival was significantly prolonged in patients with high miR-199a-1, miR-199a-2, and miR-199b expression compared with that in patients with low expression of these miRNAs (P=0.0028, P=0.0020, and P=0.0023, respectively).
