Table 5b Summary of previous published data on TERT promoter mutations in FAs and PTs
From: MED12, TERT promoter and RBM15 mutations in primary and recurrent phyllodes tumours
Publication | Number of PTs in the study | Frequency in FAs | Frequency in benign PTs | Frequency in Bo PTs | Frequency in malignant PTs | Frequency in PTs that recurred vs none recurrent cases | Evidence of acquisition of mutations in recurrent PTs | Evidence of heterogeneity in synchronous PTs/FAs |
---|---|---|---|---|---|---|---|---|
30 | NA | 0% | 33% | 60% | NA | NA | NA | |
76 | NA | 18% | 57% | 68% | NA | NA | NA | |
46 | 7% | 50% | 87% | 62% | NA | NA | NA | |
Current study | 75 primary 21 recurrences | 0% | 31% | 55% | 48% | 28 vs 50% | Yes | No |